Ethocybin has been studied as a treatment for several disorders since the early 1960s, and numerous papers are devoted to this material.[citation needed] Its short-lived action was considered a virtue. A 2010 Study showed that Ethocybin helped with bipolar affective disorder.
Effects
Ethocybin is absorbed through the lining of the mouth and stomach. Effects begin 20–45 minutes after ingestion, and last from 2–4 hours depending on dose, species, and individual metabolism.[citation needed] The effects are somewhat shorter compared to psilocybin.
Pharmacology
Ethocybin is probably metabolized mostly in the liver where it becomes ethocin, but is also broken down by the enzyme monoamine oxidase.[citation needed]
Mental and physical tolerance to psilocybin builds and dissipates quickly. Taking ethocybin more than three or four times in a week (especially two days in a row) can result in diminished effects. Tolerance dissipates after a few days, so frequent users often keep doses spaced five to seven days apart to avoid the effect.
Legality
Ethocybin is not controlled in the US, but possession or sale may be considered illegal under the Federal Analog Act.
^Gartz J (1989). "Biotransformation of tryptamine derivatives in mycelial cultures of Psilocybe". Journal of Basic Microbiology. 29 (6): 347–52. doi:10.1002/jobm.3620290608. PMID 2614674. S2CID 43308695.
^"EMCDDA | Hallucinogenic mushrooms profile (chemistry, effects, other names (magic mushrooms, shrooms…), origin, mode of use, other names, medical use, control status)". www.emcdda.europa.eu. Retrieved 2020-01-22.
^"EMCDDA | Hallucinogenic mushrooms profile (chemistry, effects, other names (magic mushrooms, shrooms…), origin, mode of use, other names, medical use, control status)". www.emcdda.europa.eu. Retrieved 2020-01-22.