User:Mr. Ibrahem/Zaleplon

Mr. Ibrahem/Zaleplon
Clinical data
Pronunciation	zal-a-plon
Trade names	Sonata, Starnoc, Andante, others
AHFS/Drugs.com	Monograph
MedlinePlus	a601251
Routes of; administration	By mouth (medical), intranasal (recreational)
Drug class	Z drug
Legal status
Legal status	UK: Class C; US: Schedule IV;
Pharmacokinetic data
Bioavailability	30% (by mouth)
Metabolism	Liver
Elimination half-life	1–1.5 h
Excretion	Kidney
Identifiers
	IUPAC name N-(3-(3-cyanopyrazolo[1,5-a] pyrimidin-7-yl)phenyl)-N-ethylacetamide;
Chemical and physical data
Formula	C17H15N5O
Molar mass	305.341 g·mol−1
3D model (JSmol)	Interactive image;
	SMILES O=C(C)N(CC)C1=CC=CC(C2=CC=NC3=C(C=NN23)C#N)=C1;
	InChI InChI=1S/C17H15N5O/c1-3-21(12(2)23)15-6-4-5-13(9-15)16-7-8-19-17-14(10-18)11-20-22(16)17/h4-9,11H,3H2,1-2H3 ; Key:HUNXMJYCHXQEGX-UHFFFAOYSA-N ;
	(verify)

Zaleplon, sold under the brand names Sonata among others, is a medication used to treat trouble sleeping.^[2] Use is not recommended for more than two weeks.^[2]^[4] It is taken by mouth.^[2]

Common side effects include headache, dizziness, and abdominal pain.^[2] Serious side effects can include sleepwalking or other complex sleep behavior, aggression, anaphylaxis, and abuse.^[2] Use is not recommended in those with significant liver problems.^[2] Safety in pregnancy and breastfeeding is unclear and such use is not recommended.^[3] It is a nonbenzodiazepine hypnotic from the pyrazolopyrimidine class.^[2]

Zaleplon was approved for medical use in the United States in 1999.^[2] In the United States it costs about 13 USD per month as of 2021.^[5] It is not currently sold in Canada and is no longer approved in the United Kingdom.^[6]^[1]

References

^ a b "Sleeping pills". www.mind.org.uk. Archived from the original on 2021-02-26. Retrieved 2021-08-04.
^ a b c d e f g h i j k "Zaleplon Monograph for Professionals". Drugs.com. Archived from the original on 17 April 2021. Retrieved 4 August 2021.
^ a b "Zaleplon (Sonata) Use During Pregnancy". Drugs.com. Archived from the original on 18 April 2021. Retrieved 4 August 2021.
^ "Zaleplon" (PDF). Archived (PDF) from the original on 29 August 2021. Retrieved 4 August 2021.
^ "Zaleplon Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 4 August 2021.
^ "Authorized Sleep-Aid Medications in Canada". www.healthycanadians.gc.ca. Archived from the original on 9 November 2017. Retrieved 4 August 2021.

[Mind2021-1] "Sleeping pills". www.mind.org.uk. Archived from the original on 2021-02-26. Retrieved 2021-08-04.

[AHFS2021-2] ^ a b c d e f g h i j k "Zaleplon Monograph for Professionals". Drugs.com. Archived from the original on 17 April 2021. Retrieved 4 August 2021.

[Preg2021-3] "Zaleplon (Sonata) Use During Pregnancy". Drugs.com. Archived from the original on 18 April 2021. Retrieved 4 August 2021.

[4] "Zaleplon" (PDF). Archived (PDF) from the original on 29 August 2021. Retrieved 4 August 2021.

[5] "Zaleplon Prices, Coupons & Savings Tips - GoodRx". GoodRx. Archived from the original on 17 May 2020. Retrieved 4 August 2021.

[6] "Authorized Sleep-Aid Medications in Canada". www.healthycanadians.gc.ca. Archived from the original on 9 November 2017. Retrieved 4 August 2021.