TECTB

TECTB
Identifiers
Aliases	TECTB, tectorin beta
External IDs	OMIM: 602653 MGI: 109574 HomoloGene: 7568 GeneCards: TECTB
Gene location (Human)
Chr.	Chromosome 10 (human)
End	112,305,038 bp
Gene location (Mouse)
Chr.	Chromosome 19 (mouse)
End	55,184,745 bp
RNA expression pattern
	Top expressed in
	retinal pigment epithelium; ; liver; ; right lobe of liver; ; right lobe of thyroid gland; ; putamen; ; temporal lobe; ; mesencephalon; ; left lobe of thyroid gland; ; substantia nigra; ; caudate nucleus;
	Top expressed in
	organ of Corti; ; utricle; ; cochlea; ; saccule; ; stria vascularis; ; brown adipose tissue; ; white adipose tissue; ; esophagus; ; stomach;
	More reference expression data
	n/a
Gene ontology
Molecular function	extracellular matrix structural constituent;
Cellular component	anchored component of membrane; membrane; extracellular region; plasma membrane; extracellular matrix;
Biological process	C-terminal protein lipidation;
	Sources:Amigo / QuickGO
Orthologs
	6975
	21684
	ENSG00000119913
	ENSMUSG00000024979
	Q96PL2
	O08524
	NM_058222
	NM_009348
	NP_478129
	NP_033374
	Wikidata
View/Edit Human	View/Edit Mouse

Beta-tectorin is a protein that in humans is encoded by the TECTB gene.^[5]

Function

The genes for alpha-tectorin and beta-tectorin (this protein) encode the major noncollagenous proteins of the tectorial membrane of the cochlea.^[5]

References

^ a b c GRCh38: Ensembl release 89: ENSG00000119913 – Ensembl, May 2017
^ a b c GRCm38: Ensembl release 89: ENSMUSG00000024979 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ a b "Entrez Gene: tectorin beta".

Legan PK, Rau A, Keen JN, Richardson GP (1997). "The mouse tectorins. Modular matrix proteins of the inner ear homologous to components of the sperm-egg adhesion system". J. Biol. Chem. 272 (13): 8791–801. doi:10.1074/jbc.272.13.8791. PMID 9079715.
Strausberg RL, Feingold EA, Grouse LH, et al. (2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc. Natl. Acad. Sci. U.S.A. 99 (26): 16899–903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
Deloukas P, Earthrowl ME, Grafham DV, et al. (2004). "The DNA sequence and comparative analysis of human chromosome 10". Nature. 429 (6990): 375–81. Bibcode:2004Natur.429..375D. doi:10.1038/nature02462. PMID 15164054.
Rose JE, Behm FM, Drgon T, et al. (2010). "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score". Mol. Med. 16 (7–8): 247–53. doi:10.2119/molmed.2009.00159. PMC 2896464. PMID 20379614.
Gerhard DS, Wagner L, Feingold EA, et al. (2004). "The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC)". Genome Res. 14 (10B): 2121–7. doi:10.1101/gr.2596504. PMC 528928. PMID 15489334.
Grupe A, Li Y, Rowland C, et al. (2006). "A scan of chromosome 10 identifies a novel locus showing strong association with late-onset Alzheimer disease". Am. J. Hum. Genet. 78 (1): 78–88. doi:10.1086/498851. PMC 1380225. PMID 16385451.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

This article on a gene on human chromosome 10 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000119913 – Ensembl, May 2017

[refGRCm38Ensembl-2] GRCm38: Ensembl release 89: ENSMUSG00000024979 – Ensembl, May 2017

[3] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[4] "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[entrez-5] "Entrez Gene: tectorin beta".

TECTB

Function

References

Further reading