The island forms part of the Arvia'juaq and Qikiqtaarjuk National Historic Site and a Paallirmiut Inuit summer camp site. Sentry Island is a popular place for fishing and hunting.
The island served as a rest stop for Henry Hudson and his crew during his ill-fated journeys to find the Northwest Passage in 1610 - 1611.
On July 3, 2018, a man from Arviat was killed in a rare polar bear attack on the island. The man was on the island with his children when the polar bear approached them and attacked, killing 31-year-old Aaron Gibbons. The bear was killed by two others who were living in the area.
- "Sentry Island, Nunavut, Canada". travelingluck.com. Retrieved 2008-12-03.
- Arvia’juaq National Historic Site Archived 2008-05-17 at the Wayback Machine
- "Man killed in polar bear attack 'died a hero,' says cousin". CBC News. July 4, 2018.
- "Canadian man killed in rare polar bear attack". BNO News. July 4, 2018.