Protein BEX2

BEX2
Identifiers
AliasesBEX2, BEX1, DJ79P11.1, brain expressed X-linked 2
External IDsOMIM: 300691 MGI: 1338017 HomoloGene: 135604 GeneCards: BEX2
Orthologs
SpeciesHumanMouse
Entrez
Ensembl
UniProt
RefSeq (mRNA)

NM_032621
NM_001168399
NM_001168400
NM_001168401

NM_009749

RefSeq (protein)

NP_001161871
NP_001161872
NP_001161873
NP_116010

NP_033879

Location (UCSC)Chr X: 103.31 – 103.31 MbChr X: 134.97 – 134.97 Mb
PubMed search[3][4]
Wikidata
View/Edit HumanView/Edit Mouse

Protein BEX2 also known as brain-expressed X-linked protein 2 is a protein that in humans is encoded by the BEX2 gene.[5][6]

References

  1. ^ a b c GRCh38: Ensembl release 89: ENSG00000133134 – Ensembl, May 2017
  2. ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000042750 – Ensembl, May 2017
  3. ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  4. ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
  5. ^ Strausberg RL, Feingold EA, Grouse LH, Derge JG, Klausner RD, Collins FS, Wagner L, Shenmen CM, Schuler GD, Altschul SF, Zeeberg B, Buetow KH, Schaefer CF, Bhat NK, Hopkins RF, Jordan H, Moore T, Max SI, Wang J, Hsieh F, Diatchenko L, Marusina K, Farmer AA, Rubin GM, Hong L, Stapleton M, Soares MB, Bonaldo MF, Casavant TL, Scheetz TE, Brownstein MJ, Usdin TB, Toshiyuki S, Carninci P, Prange C, Raha SS, Loquellano NA, Peters GJ, Abramson RD, Mullahy SJ, Bosak SA, McEwan PJ, McKernan KJ, Malek JA, Gunaratne PH, Richards S, Worley KC, Hale S, Garcia AM, Gay LJ, Hulyk SW, Villalon DK, Muzny DM, Sodergren EJ, Lu X, Gibbs RA, Fahey J, Helton E, Ketteman M, Madan A, Rodrigues S, Sanchez A, Whiting M, Madan A, Young AC, Shevchenko Y, Bouffard GG, Blakesley RW, Touchman JW, Green ED, Dickson MC, Rodriguez AC, Grimwood J, Schmutz J, Myers RM, Butterfield YS, Krzywinski MI, Skalska U, Smailus DE, Schnerch A, Schein JE, Jones SJ, Marra MA (Dec 2002). "Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences". Proc Natl Acad Sci U S A. 99 (26): 16899–16903. Bibcode:2002PNAS...9916899M. doi:10.1073/pnas.242603899. PMC 139241. PMID 12477932.
  6. ^ "Entrez Gene: BEX2 brain expressed X-linked 2".

Further reading

  • Baldisseri DM, Margolis JW, Weber DJ, et al. (2002). "Olfactory marker protein (OMP) exhibits a beta-clam fold in solution: implications for target peptide interaction and olfactory signal transduction". J. Mol. Biol. 319 (3): 823–837. doi:10.1016/S0022-2836(02)00282-6. PMID 12054873.
  • Alvarez E, Zhou W, Witta SE, Freed CR (2005). "Characterization of the Bex gene family in humans, mice, and rats". Gene. 357 (1): 18–28. doi:10.1016/j.gene.2005.05.012. PMID 15958283.
  • Han C, Liu H, Liu J, et al. (2005). "Human Bex2 interacts with LMO2 and regulates the transcriptional activity of a novel DNA-binding complex". Nucleic Acids Res. 33 (20): 6555–6565. doi:10.1093/nar/gki964. PMC 1298925. PMID 16314316.
  • Foltz G, Ryu GY, Yoon JG, et al. (2006). "Genome-wide analysis of epigenetic silencing identifies BEX1 and BEX2 as candidate tumor suppressor genes in malignant glioma". Cancer Res. 66 (13): 6665–6674. doi:10.1158/0008-5472.CAN-05-4453. PMID 16818640.
  • Fischer C, Drexler HG, Reinhardt J, et al. (2007). "Epigenetic regulation of brain expressed X-linked-2, a marker for acute myeloid leukemia with mixed lineage leukemia rearrangements". Leukemia. 21 (2): 374–377. doi:10.1038/sj.leu.2404493. PMID 17251904. S2CID 30361206.
  • Naderi A, Teschendorff AE, Beigel J, et al. (2007). "BEX2 is overexpressed in a subset of primary breast cancers and mediates nerve growth factor/nuclear factor-kappaB inhibition of apoptosis in breast cancer cell lines". Cancer Res. 67 (14): 6725–6736. doi:10.1158/0008-5472.CAN-06-4394. PMID 17638883.


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