Picloxydine

Picloxydine
Names
IUPAC name
1-N',4-N'-bis[N'-(4-chlorophenyl)carbamimidoyl]piperazine-1,4-dicarboximidamide
Identifiers
  • 5636-92-0 checkY
3D model (JSmol)
  • Interactive image
ChEMBL
  • ChEMBL2104722 ☒N
ChemSpider
  • 64722 ☒N
ECHA InfoCard 100.024.623
  • 71663
UNII
  • 4YC2PY3AEU checkY
  • InChI=1S/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30) ☒N
    Key: YNCLPFSAZFGQCD-UHFFFAOYSA-N ☒N
  • InChI=1/C20H24Cl2N10/c21-13-1-5-15(6-2-13)27-17(23)29-19(25)31-9-11-32(12-10-31)20(26)30-18(24)28-16-7-3-14(22)4-8-16/h1-8H,9-12H2,(H4,23,25,27,29)(H4,24,26,28,30)
    Key: YNCLPFSAZFGQCD-UHFFFAOYAM
  • C1CN(CCN1C(=NC(=NC2=CC=C(C=C2)Cl)N)N)C(=NC(=NC3=CC=C(C=C3)Cl)N)N
Properties
C20H24Cl2N10
Molar mass 475.37756
Pharmacology
S01AX16 (WHO)
Except where otherwise noted, data are given for materials in their standard state (at 25 °C [77 °F], 100 kPa).
☒N verify (what is checkY☒N ?)

Picloxydine (trade name Vitabact[1]) is a bisbiguanide antiseptic used in eye drops. It is structurally similar to chlorhexidine.

References

  1. ^ Obikili AG, Oji EO, Shonekan RO, Otti P (1988). "A double-blind comparison of picloxydine dihydrochloride (Vitabact eye drops) and sulfacetamide eye drops in the topical therapy of trachoma". Revue Internationale du Trachome et de Pathologie Oculaire Tropicale et Subtropicale et de Santé Publique. 65 (3–4): 119–32. PMID 3274675.


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