OBSL1

OBSL1
Available structures
PDB	Human UniProt search: PDBe RCSB
List of PDB id codes
	2CPC, 2E6P, 2E6Q, 2LU7, 2LVC, 2WP3, 2WWK, 2WWM, 3KNB
Identifiers
Aliases	OBSL1, obscurin like 1, obscurin like cytoskeletal adaptor 1
External IDs	OMIM: 610991 HomoloGene: 28013 GeneCards: OBSL1
Gene location (Human)
Chr.	Chromosome 2 (human)
End	219,571,859 bp
RNA expression pattern
	Top expressed in
	right lobe of thyroid gland; ; left lobe of thyroid gland; ; right uterine tube; ; anterior pituitary; ; left uterine tube; ; canal of the cervix; ; body of pancreas; ; gastric mucosa; ; left ventricle; ; tibial nerve;
	n/a
	More reference expression data
	; ; ; ;
	More reference expression data
Gene ontology
Molecular function	cytoskeletal anchor activity; protein binding; structural constituent of muscle; actin filament binding; muscle alpha-actinin binding; structural molecule activity conferring elasticity;
Cellular component	Z disc; 3M complex; intercalated disc; M band; centrosome; microtubule organizing center; cytoskeleton; cytoplasm; Golgi apparatus; perinuclear region of cytoplasm; muscle myosin complex; cytosol; striated muscle thin filament; sarcomere;
Biological process	protein localization to Golgi apparatus; cardiac myofibril assembly; microtubule cytoskeleton organization; cytoskeleton organization; regulation of mitotic nuclear division; positive regulation of dendrite morphogenesis; Golgi organization; striated muscle contraction; actin filament organization; sarcomere organization; striated muscle myosin thick filament assembly; post-translational protein modification; muscle contraction; skeletal muscle thin filament assembly; skeletal muscle myosin thick filament assembly; cardiac muscle tissue morphogenesis;
	Sources:Amigo / QuickGO
Orthologs
	23363
	n/a
	ENSG00000124006
	n/a
	O75147
	n/a
	NM_001173408; NM_001173431; NM_015311
	n/a
	NP_001166879; NP_001166902; NP_056126
	n/a
	Wikidata
View/Edit Human

Obscurin-like protein 1 is a protein that in humans is encoded by the OBSL1 gene.^[3]^[4]

References

^ a b c GRCh38: Ensembl release 89: ENSG00000124006 – Ensembl, May 2017
^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
^ Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.
^ "Entrez Gene: OBSL1 obscurin-like 1".

External links

GeneReviews/NIH/NCBI/UW entry on 3-M syndrome
OMIM entries on 3-M syndrome
PDBe-KB provides an overview of all the structure information available in the PDB for Human Obscurin-like protein 1 (OBSL1)

This article on a gene on human chromosome 2 is a stub. You can help Wikipedia by expanding it.

[refGRCh38Ensembl-1] GRCh38: Ensembl release 89: ENSG00000124006 – Ensembl, May 2017

[2] "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.

[pmid9734811-3] Ishikawa K, Nagase T, Suyama M, Miyajima N, Tanaka A, Kotani H, Nomura N, Ohara O (Dec 1998). "Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro". DNA Res. 5 (3): 169–76. doi:10.1093/dnares/5.3.169. PMID 9734811.

[entrez-4] "Entrez Gene: OBSL1 obscurin-like 1".

OBSL1

References

Further reading

External links