Motor protein found in humans
KIF19 |
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Identifiers |
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Aliases | KIF19, KIF19A, kinesin family member 19 |
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External IDs | MGI: 2447024 HomoloGene: 17709 GeneCards: KIF19 |
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Gene location (Mouse) |
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| Chr. | Chromosome 11 (mouse)[2] |
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| Band | 11|11 E2 | Start | 114,656,214 bp[2] |
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End | 114,681,565 bp[2] |
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RNA expression pattern |
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Bgee | Human | Mouse (ortholog) |
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Top expressed in | - right uterine tube
- sural nerve
- spleen
- hypothalamus
- amygdala
- caudate nucleus
- putamen
- bronchial epithelial cell
- Brodmann area 9
- substantia nigra
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| Top expressed in | - islet of Langerhans
- spermatocyte
- hypothalamus
- testicle
- lens
- ovary
- spermatid
- morula
- quadriceps femoris muscle
- olfactory bulb
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| More reference expression data |
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BioGPS | |
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Gene ontology |
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Molecular function |
- microtubule binding
- microtubule motor activity
- nucleotide binding
- ATPase activity
- plus-end-directed microtubule motor activity
- ATP binding
| Cellular component |
- cytoplasm
- axoneme
- cell projection
- cilium
- microtubule
- cytoskeleton
- kinesin complex
| Biological process |
- microtubule-based movement
- axonemal microtubule depolymerization
- plus-end specific microtubule depolymerization
| Sources:Amigo / QuickGO |
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Wikidata |
View/Edit Human | View/Edit Mouse |
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Kinesin family member 19 (KIF19) is a protein in humans encoded by the KIF19 gene. It is part of the kinesin family of motor proteins.
Function
KIF19 is involved in cancer metastasis, as well as cell-cell and cell-matrix interactions.[5]
References
- ^ a b c GRCh38: Ensembl release 89: ENSG00000196169 – Ensembl, May 2017
- ^ a b c GRCm38: Ensembl release 89: ENSMUSG00000010021 – Ensembl, May 2017
- ^ "Human PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ "Mouse PubMed Reference:". National Center for Biotechnology Information, U.S. National Library of Medicine.
- ^ Eisenberg, Samuel C.; Dey, Abhinav; Birnbaum, Rayna; Sharp, David J. (2020-09-04). "The kinesin-8 member Kif19 alters microtubule dynamics, suppresses cell adhesion, and promotes cancer cell invasion". doi:10.1101/2020.09.04.282657. S2CID 221589215.