File:Lead poisoning - blood film.jpg
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Summary
| Description |
English: Image's description reads: "Lead poisoning: Peripheral blood film from an anemic 53-year-old geophysicist who complained of fatigue and constipation. The blood film of his asymptomatic wife showed similar changes, but that of his 12-year-old son was normal.
Basophilic stippling of this patient’s red cells (image below, arrows) suggested lead poisoning. Despite repeated inquiry, however, no source for such poisoning emerged. The plot thickened when blood lead concentrations were substantially elevated in both the man and his wife but normal in their son. Continued sleuthing ultimately unveiled the culprit — cocktail glasses decorated with lead-based paint. The husband and wife drank from these glasses daily, but their son never drank from them. Washing the glasses by machine presumably caused leaching of lead salts. Chelation therapy for the two adults returned their hematologic findings to normal, and the patient became asymptomatic. Moral: Basophilic stippling of red cells can be the first, best, or only clue to lead poisoning." Français : Description de l'image originale : "L'empoisonnement au plomb" : Vue au microscope d'un échantillon sanguin (de sang périphérique) prélevé chez un géophysicien de 53 ans victime d'anémie, et qui se plaignait de fatigue et de constipation. L'observation du sang de sa femme (asymptomatique) présentait des anomalies similaires, mais celle de son fils de 12 ans était normale. une ponctuations basophile des globules rouges (voir image)a chez ce patient suggéré un empoisonnement au plomb. Malgré des enquêtes répétées cependant, aucune source pour cette intoxication n'a émergé. L'intrigue s'est épaissie quand on a constaté que les plombémies étaient anormalement élevées à la fois le mari et la femme, mais normale chez leur enfant. L'enquête a finalement révélé le coupable ; il s'agissait de verres à cocktail décorés avec une peinture à base de plomb, que seuls les parents utilisaient. Son nettoyage à la machine à laver la vaisselle pourrait avoir causé une lixiviation des sels de plomb. Une thérapie par chélation a été mise en place pour les deux adultes qui ont ensuite retrouvé des résultats hématologiques normaux, et le patient est devenu asymptomatique. Moralité: une ponctuations basophiles des globules rouges peut être le premier, le meilleur, ou seul indice au saturnisme" |
| Source | http://cnx.org/content/m15003/latest/ |
| Author | Herbert L. Fred, MD and Hendrik A. van Dijk |
| Permission (Reusing this file) |
This work is licensed under a Creative Commons Attribution License (CC-BY 2.0). |
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File history
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| Date/Time | Thumbnail | Dimensions | User | Comment | |
|---|---|---|---|---|---|
| current | 09:24, 9 March 2020 | 578 × 266 (29 KB) | Sebastian Wallroth | Cropped 6 % horizontally, 12 % vertically using CropTool with lossless mode. Removed border. | |
| 17:11, 21 October 2008 | 617 × 303 (29 KB) | PhilippN | == Beschreibung == {{Information |Description=Lead poisoning: Peripheral blood film from an anemic 53-year-old geophysicist who complained of fatigue and constipation. The blood film of his asymptomatic wife showed similar changes, but that of his 12-year |
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