File:DHFR methotrexate inhibitor.png

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Summary

Description
English: An enzyme binding site that would normally bind substrate can alternatively bind a competitive inhibitor, preventing substrate access. Dihydrofolate reductase is inhibited by methotrexate which prevents binding of its substrate, folic acid. Binding site in blue, inhibitor in green, and substrate in black. (PDB: 4QI9​)
Date
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Author Thomas Shafee
Other versions For vector version, see File:DHFR methotrexate inhibitor.svg

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author name string: Thomas Shafee
Wikimedia username: Evolution and evolvability
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inception

6 March 2015

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Date/TimeThumbnailDimensionsUserComment
current20:53, 4 October 2016914 × 861 (176 KB)CmdrjamesonCompressed with pngout. Reduced by 93kB (34% decrease).
11:35, 6 March 2015914 × 861 (269 KB)Evolution and evolvabilityUser created page with UploadWizard
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