Dapiprazole

Dapiprazole
Clinical data
AHFS/Drugs.comConsumer Drug Information
MedlinePlusa601043
Pregnancy
category
  • B
Routes of
administration		Topical (eye drops)
ATC code
Legal status
Legal status
  • In general: ℞ (Prescription only)
Pharmacokinetic data
BioavailabilityNegligible when administered topically
Identifiers
  • 3-{2-[4-(2-methylphenyl)piperazin-1-yl]ethyl}-5,6,7,8-tetrahydro-[1,2,4]triazolo[4,5-a]pyridine
CAS Number
  • 72822-12-9 checkY
PubChem CID
  • 3033538
IUPHAR/BPS
  • 7155
DrugBank
  • DB00298 checkY
ChemSpider
  • 2298190 checkY
UNII
  • 5RNZ8GJO7K
KEGG
  • D07775 checkY
ChEBI
  • CHEBI:51066 checkY
ChEMBL
  • ChEMBL1201216 ☒N
CompTox Dashboard (EPA)
  • DTXSID90223140
Chemical and physical data
FormulaC19H27N5
Molar mass325.460 g·mol−1
3D model (JSmol)
  • Interactive image
  • n1nc(n2c1CCCC2)CCN4CCN(c3ccccc3C)CC4
  • InChI=1S/C19H27N5/c1-16-6-2-3-7-17(16)23-14-12-22(13-15-23)11-9-19-21-20-18-8-4-5-10-24(18)19/h2-3,6-7H,4-5,8-15H2,1H3 checkY
  • Key:RFWZESUMWJKKRN-UHFFFAOYSA-N checkY
 ☒NcheckY (what is this?)  (verify)

Dapiprazole (brand name Rev-Eyes) is an alpha-1 blocker. It is used to reverse mydriasis after eye examination.[1]

References

  1. ^ Doughty MJ, Lyle WM (May 1992). "A review of the clinical pharmacokinetics of pilocarpine, moxisylyte (thymoxamine), and dapiprazole in the reversal of diagnostic pupillary dilation". Optometry and Vision Science. 69 (5): 358–68. doi:10.1097/00006324-199205000-00005. PMID 1350669. S2CID 22781280.


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