Defending champion William Larned defeated Tom Bundy in the Challenge Round 6–1, 5–7, 6–0, 6–8, 6–1 to win the men's singles tennis title at the 1910 U.S. National Championships.[2] Bundy defeated Beals Wright in the All Comers' Final.[3]
The event was held at the Newport Casino in Newport, R.I. in the United States.[1][4]